The Tom and Jerry custered pie meme came from the original Tom and Jerry show's "Quite Please"  Episode. In the episode, Spike is trying to take a nap and is disturbed by the noises Tom makes while chasing Jerry.

In the particular Meme's scenario. Jerry writes a will, giving Tom his sole possession, that is "A Custard Pie". Just at the moment Tom says Let Me Have it, Jerry throws the Custard pie at Tom's face.

This meme has four screenshots from the scene and is famous among the meme community. It has been shared millions of times online on socia media.